There are a couple things I've done to tweak World of Warcraft on my Linux box. I run OpenSuse 10.3 now but most of this will be the same for other distros, especially if you use KDE. These are just specific to what worked for me but I guess that some other Linux WoW players might benefit from the same settings.
First off I lost the ability to do a quick self-cast. Self-cast is done by just holding alt while clicking the icon for a spell. So, as a mage, every half-hour I want to self-cast Arcane Intellect. That's no big deal since it's not in combat. Remove Lesser Curse is a bigger problem. The second fastest way to use that is with a shortcut key or click followed by F1 (which also targets your own character). I thought the problem was because of some multi-language keyboard customization I had done but as it turns out it was a setting in KDE for moving windows by holding the Alt-key. To turn this off just follow the steps here - I included pictures, click each to get a bigger image.
1.In KDE, choose Personal Settings (Configure Desktop) from your system menu.
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2. Pick Desktop on the left side then Window Behavior. In the tabs across the top pick Window Actions. The default Window Actions settings have a few options turned on so that you can hold alt and click inside a window to move that window. I've never used this feature except in the five minutes after I found out about it.
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3. I just turned off all the Inner Window, Titlebar and Frame actions by setting the drop-down choice to "Nothing".
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The second tweak, and I think this made a big performance improvement in my case, was to set Wine up to run inside a single window. World of Warcraft still thinks it's running full-screen but it's running in the full area that Wine provides. To configure options for Wine, go to a console and run winecfg. The option I turned on is called "Emulate a Virtual Desktop" option and it's on the Graphics tab. My screen resolution is at 1280x1024 but I gave Wine a window of 1024x768. The performance seems much better now, especially when switching from WoW to a browser or another application.
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